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The Incubator Fund provides seed funding to support novel or exploratory interdisciplinary research into any aspect of reproduction. The scheme began in March 2021, with generous support from the Isaac Newton Trust, and has supported the following projects:

 

2020-2021

Developing an in vitro system to study epigenetics in human placental trophoblast cells

Dr Courtney Hanna (CTR/Babraham Institute) and Dr Vicente Perez-Garcia (CTR/PDN)

Epigenetics is essential for cell identity and differentiation during development. Yet, little is known about how these processes are involved in regulating placental development in human pregnancy. We propose to develop and validate an in vitro organoid system to grow multipotent human placental trophoblast cells.

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Brain Activation in Mother and BabY (BAMBY)

Grace Kromm (Clinical Neurosciences), Dr Vicky Leong (Psychology) and Professor Topun Austin (Paediatrics)

The BAMBY study aims to characterise neural synchrony between mothers and their babies in the neonatal environment and associate this neural synchrony with salient neurological, physiological, and behavioural measures to provide important insight into early social and emotional development.

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NICU and rapid genetic testing: Comparing mothers’ and fathers’ views and experiences

Helen Dolling (Psychology/CFR), Professor Claire Hughes (Psychology/CFR) and Dr Kate Baker (MRC CBU/Department of Clinical Genetics, CUH)

This project expands an existing interview-based study of parental experiences of rapid genetic testing for neonates with serious health problems through additional interviews with fathers. We aim to transform clinical practice via enhanced understanding of interactions between genetics, reproduction and family life.

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