skip to content

Cambridge Reproduction


My research focuses on the embryonic development of the mammalian germline. In humans and mice, the germline segregates from somatic cell linages within the early post-implantation embryo and undergoes epigenetic resetting as part of a “rejuvenation” process laying the foundation for the subsequent life cycle. In my research, I employ human and murine embryonic stem cell-based in vitro systems recapitulating the germline-soma segregation in vivo as well as transcriptional and epigenetic analysis of in vivo primordial germ cells to understand the molecular mechanism driving germline specification and development.